Buy Tarka (Trandolapril/Verapamil) Online From Medications Canada.

About Tarka

Uses and Benefits of Tarka

Tarka is indicated for the treatment of high blood pressure. This combination medicine is not recommended as the first treatment for hypertension. When using Tarka, consider that captopril, another ACE inhibitor, has caused agranulocytosis, especially in patients with kidney disease or collagen vascular disease. There is not enough data to confirm that trandolapril carries the same risk.

Ingredients in Tarka

The active ingredients in Tarka are trandolapril and verapamil hydrochloride. Trandolapril is in an immediate-release form, while verapamil hydrochloride is in a controlled-release form. The available strengths are trandolapril 2 mg/verapamil hydrochloride ER 180 mg, trandolapril 1 mg/verapamil hydrochloride ER 240 mg, trandolapril 2 mg/verapamil hydrochloride ER 240 mg, and trandolapril 4 mg/verapamil hydrochloride ER 240 mg.

Inactive ingredients include corn starch, dioctyl sodium sulfosuccinate, ethanol, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, purified water, silicon dioxide, sodium alginate, sodium stearyl fumarate, synthetic iron oxides, talc, and titanium dioxide.

How to Take Tarka?

Follow your doctor’s prescription exactly.

The usual dose of trandolapril for high blood pressure is 1 to 4 mg daily, taken as one or two doses. The usual dose of verapamil (Isoptin-SR) for high blood pressure is 120 to 480 mg daily, taken as one or two doses.

Start Tarka only after trying trandolapril and verapamil separately. You should have taken the maximum recommended dose of each at the shortest dosing interval. If you cannot increase the dose of one medicine due to side effects, your doctor may recommend Tarka.

Studies have tested Tarka in once-daily doses. Some dose combinations have not been studied, including trandolapril 4 mg once daily with verapamil 240 mg twice daily or trandolapril 2 mg twice daily with verapamil 180 mg once daily. The effects of Tarka increase with higher doses of either medicine.

If you are switching from separate trandolapril and verapamil doses, your Tarka dose should match them. Take Tarka with food.

Who Should Not Take Tarka?

Do not take Tarka if you are allergic to any ACE inhibitor or verapamil. Because of the verapamil component, do not use Tarka if you have severe left ventricular dysfunction. It is also contraindicated if you have low blood pressure (systolic pressure below 90 mmHg) or cardiogenic shock.

Do not take Tarka if you have sick sinus syndrome, unless you have a functioning pacemaker. It is also not recommended if you have second- or third-degree AV block, unless you have a functioning pacemaker. Do not take Tarka if you have atrial flutter or atrial fibrillation with an accessory bypass tract, such as Wolff-Parkinson-White or Lown-Ganong-Levine syndrome. Because of the trandolapril component, do not use Tarka if you have had angioedema from an ACE inhibitor.

Side Effects of Tarka

Common side effects may include:

• Drowsiness
• Insomnia
• Diarrhea
• Nausea
• Rash

Serious side effects may include:

• Low blood pressure (hypotension) or fainting
• Heart rhythm problems, such as AV block
• Myocardial infarction (heart attack)
• Severe allergic reactions such as angioedema
• Shortness of breath (dyspnea)

This is not a complete list of possible side effects. For a complete list, ask your doctor or pharmacist.

Safety Precautions

Before you take Tarka, tell your healthcare provider if you have heart failure, low blood pressure, or liver disease. Also, mention if you have kidney problems, neuromuscular conditions, or any other medical issues.

Tell your healthcare provider if you have a history of allergic reactions, especially to ACE inhibitors. Trandolapril can cause life-threatening angioedema. Stop taking Tarka and seek immediate medical help if you have swelling in your face, throat, or tongue.

Verapamil can worsen heart failure. Avoid it in severe left ventricular dysfunction or when taking beta-blockers. Trandolapril may cause low blood pressure, especially in heart failure patients.

Both verapamil and trandolapril can lower blood pressure, particularly if you are dehydrated or have low salt levels. Correct these issues before starting Tarka. If you feel dizzy or faint, lie down and seek medical help if needed.

Tarka can affect liver function. Verapamil may raise liver enzyme levels, while trandolapril can cause rare but serious liver problems. Your doctor may monitor your liver function during treatment.

Verapamil can cause dangerous heart rhythms in patients with atrial fibrillation or flutter with an accessory AV pathway. Do not take Tarka if you have this condition. It can also lead to AV block. If this occurs, your doctor may reduce the dose or stop treatment.

Patients with hypertrophic cardiomyopathy should use verapamil with caution, as it may worsen their condition.

Trandolapril may lower white blood cell counts, increasing the risk of infections. If you have collagen-vascular disease or kidney disease, your doctor may monitor your white blood cell levels.

Tarka can harm an unborn baby. Do not take it if you are pregnant. Tell your doctor immediately if you become pregnant while using this medication.

If you have liver or kidney disease, you may need a lower dose of Tarka. Your doctor will monitor your condition closely.

Verapamil may affect neuromuscular transmission, which could be a concern in certain conditions or when taken with specific medications.

Trandolapril can raise potassium levels. Be cautious if you take potassium supplements or potassium-sparing diuretics.

A persistent cough may occur with trandolapril. This usually stops when you discontinue the medication.

Tarka can affect blood pressure during surgery or anesthesia. Inform your doctor before any medical procedures.

Tarka interacts with many medications, including digitalis, lithium, certain antibiotics, antiarrhythmics, antihypertensives, and beta-blockers. Other interactions include diuretics, potassium-increasing agents, statins, NSAIDs, nitrates, and carbamazepine. Tell your healthcare provider about all prescription and nonprescription medications, vitamins, and herbal supplements you take.

Avoid grapefruit juice while taking verapamil. Tarka may also interact with immunosuppressants, tranquilizers, and anti-diabetic medications.

Studies show no link between Tarka’s ingredients and cancer or fertility problems.

Do not take Tarka if you are breastfeeding. Use caution if you are elderly. The safety of Tarka in children has not been established.

Storage Guidelines

Store Tarka at room temperature between 15°C and 25°C in a dry place. Keep the medication away from moisture and direct sunlight. Do not freeze, as this may affect its effectiveness. Keep Tarka out of the reach and sight of children to prevent accidental ingestion. Check the expiration date on the packaging and do not use the medication after this date. Dispose of expired or unused Tarka according to local regulations or ask your pharmacist for proper disposal instructions.

FAQs

How long does it take to receive Tarka when ordering online?

It takes approximately 2 to 4 weeks for shipping Tarka after it leaves the pharmacy.

Is a prescription required to buy Tarka online?

Yes, a valid prescription is required to buy Tarka online.

What payment options are available for purchasing Tarka online?

We take payments by personal check, certified check, international money order, and e-check.

What is the refund or return policy for Tarka Bought online?

Pharmaceutical laws and safety rules prevent us from accepting returns or issuing refunds for Tarka bought online. Always consult your doctor before ordering. Read more.

Is Tarka available over-the-counter?

Tarka is not available over the counter because it needs to be used under a doctor’s supervision. Due to the risk of serious side effects, like hypotension, a valid prescription is required to ensure safe use.

Reference

• MedlinePlus. High Blood Pressure. https://medlineplus.gov/highbloodpressure.html
• FDA. Label. Tarka (trandolapril/verapamil hydrochloride ER tablets). https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020591s030lbl.pdf
• Health Canada. Tarka Product Monograph. https://pdf.hres.ca/dpd_pm/00003595.PDF