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Formulation : Capsule
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Prescription Prescription Required
Formulation : Capsule
Drug Name Dosage Quantity Price Buy Now
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About Sinequan (Doxepin Hydrochloride)

Uses and Benefits of Sinequan (Doxepin Hydrochloride)

Sinequan (Doxepin Hydrochloride) is indicated for the treatment of mental health conditions such as depression and anxiety. It helps improve mood, relieve anxiety, reduce tension, and enhance sleep quality. It may also increase energy levels and overall well-being. This medication belongs to a class of drugs called tricyclic antidepressants. It works by balancing specific brain chemicals, including serotonin and norepinephrine, that regulate mood and emotions.

Ingredients in Sinequan (Doxepin Hydrochloride)

The active ingredient in Sinequan is doxepin hydrochloride, with a dose of 3 mg of doxepin per tablet. Inactive ingredients include: Silicon dioxide, croscarmellose sodium, anhydrous dibasic calcium phosphate, hypromellose, magnesium stearate, microcrystalline cellulose, and titanium dioxide.

How to Take Sinequan (Doxepin Hydrochloride)?

Follow your doctor’s prescription exactly. Sinequan (Doxepin Hydrochloride) is usually taken 1 to 3 times daily, with or without food. If prescribed once daily, take it before bedtime to reduce daytime drowsiness.

Always follow your doctor’s advice about the timing and dosage of your medication.

Who Should Not Take Sinequan (Doxepin Hydrochloride)?

Do not take Sinequan (Doxepin Hydrochloride) if you are allergic to doxepin or have had a hypersensitivity reaction to the medication. Be aware of possible cross-sensitivity with other dibenzoxepines.

Do not take Sinequan if you have glaucoma or a tendency to urinary retention. These conditions should be ruled out before starting treatment, especially in older adults.

Always consult your doctor for guidance.

Side Effects of Sinequan (Doxepin Hydrochloride)

Common Side Effects:

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Constipation
  • Headache

Serious Side Effects:

  • Changes in blood pressure
  • Rapid heart rate
  • Difficulty urinating
  • Fainting
  • Jaundice

Contact your doctor if you experience any other unlisted side effects. For a complete list, consult your doctor or pharmacist.

Safety Precautions for Sinequan (Doxepin Hydrochloride)

Before taking Sinequan, inform your healthcare provider if you have allergies to doxepin, tricyclic antidepressants (e.g., nortriptyline), or other medications. Also, disclose if you have bleeding disorders, liver problems, respiratory issues, or a history of a recent heart attack.

Let your provider know if you experience urinary difficulties, have hyperthyroidism, or have a family history of angle-closure glaucoma. Additionally, mention any personal or family history of mood disorders, suicide, seizures, or conditions that increase seizure risk.

Tell your healthcare provider about any current, recently started, or stopped medications, including prescription drugs, nonprescription drugs, vitamins, or herbal supplements, to lower the risk of drug interactions with Sinequan.

Some medications may interact with Sinequan, such as:

  • Arbutamine
  • thyroid supplements
  • certain hypertension medications (e.g., clonidine)

The combination of Sinequan and MAO inhibitors can lead to a potentially life-threatening drug interaction. Avoid concurrent use of MAO inhibitors listed below while treatment with this medication:

  • Isocarboxazid
  • Linezolid
  • Metaxalone
  • Methylene blue
  • Moclobemide
  • Phenelzine
  • Procarbazine
  • Rasagiline
  • Safinamide
  • Selegiline
  • Tranylcypromine

Avoid MAO inhibitors during Sinequan treatment and for 2 weeks before and after.

Certain medications can impact the elimination of Sinequan from the system, consequently influencing its effectiveness. Examples of such drugs include:

  • cimetidine
  • St. John’s Wort
  • antidepressants like SSRIs (e.g., paroxetine, fluoxetine)
  • medications for irregular heart rhythm

Ensure to review the labels of all your medications, including allergy and cough-and-cold products, as they might contain decongestants or drowsiness-inducing ingredients. Consult your pharmacist for guidance on the safe usage of such products.

Inform your healthcare provider or pharmacist if you are using any other products that induce drowsiness, including:

  • Opioid pain or cough medications (e.g., codeine, hydrocodone)
  • Alcohol
  • Marijuana (cannabis)
  • Sleep or anxiety medications (e.g., alprazolam, lorazepam, zolpidem)
  • Muscle relaxants (e.g., carisoprodol, cyclobenzaprine)
  • Antihistamines (e.g., cetirizine, diphenhydramine)

Additional Cautions

Sinequan may cause drowsiness. Avoid driving or using machinery until you know its effects. It can increase sun sensitivity; use sunscreen and wear protective clothing outdoors. Immediately inform your doctor of any sunburn or skin inflammation

For people with diabetes, Sinequan may affect blood sugar control. Monitor levels and consult your doctor if changes occur. If you have asthma, inform your doctor, as Sinequan may worsen symptoms.

Pregnancy and Breastfeeding

Sinequan should only be used during pregnancy if necessary. Infants born to mothers who took this medication in the final trimester may occasionally experience withdrawal symptoms, including issues with feeding and breathing, seizures, muscle stiffness, or persistent crying. Promptly inform your doctor if you observe any of these signs in your newborn.

Do not breastfeed while taking Sinequan, as it passes into breast milk and may harm the baby.

Storage Guidelines for Sinequan (Doxepin Hydrochloride)

Store Sinequan at room temperature between 20°C and 25°C (68°F to 77°F). Protect the medication from light to maintain its effectiveness. Keep Sinequan in a tightly sealed, light-resistant container as recommended by the USP. Use a child-resistant closure to ensure safety.

Keep the medication out of the reach and sight of children. For disposal of unused or expired medication, consult your pharmacist or follow local disposal guidelines.

FAQs

How long does it take to receive Sinequan when ordering prices?

It takes approximately 2 to 4 weeks for shipping Sinequan after it leaves the pharmacy.

Is a prescription required to buy Sinequan online?

Yes, a valid prescription is required to buy Sinequan online.

What payment options are available for purchasing Sinequan online?

We take payments by personal check, certified check, international money order, and e-check.

What is the refund or return policy for Sinequan bought online?

Pharmaceutical laws and safety rules prevent us from accepting returns or issuing refunds for Sinequan bought online. Always consult your doctor before ordering. Read more.

Is Sinequan available over-the-counter?

Sinequan is not available over the counter because it needs to be used under a doctor’s supervision. Due to the risk of serious side effects, like arrhythmia, a valid prescription is required to ensure safe use.

Reference

  • U.S. Food and Drug Administration. Sinequan (doxepin hydrochloride). https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/016798s054,017516s023lbl.pdf
  • National Institute of Mental Health. Anxiety Disorders. https://www.nimh.nih.gov/health/topics/anxiety-disorders
  • Drugs.com. Sinequan. https://www.drugs.com/cons/sinequan.html

Additional information

Scientific Name:

Doxepin, Doxepin Hydrochloride

Formulation:

Capsule

Strength(s):

10mg, 25mg, 50mg, 75mg, 100mg

Quantities Available:

100

MedicationsCanada.com receives the above information for Sinequan (Doxepin Hydrochloride) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.