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Description

What is Pradaxa?

Pradaxa (dabigatran etexilate mesylate) is an oral direct thrombin inhibitor indicated to reduce the risk of stroke and systemic blood clots among patients with non-valvular atrial fibrillation. This drug works by impeding thrombus formation through the inhibition of thrombin from converting fibrinogen into fibrin during the coagulation cascade. As a result, it could treat and prevent deep vein thrombosis or pulmonary embolism.

The medication is available in 75 mg and 150 mg capsules.

Directions in using Pradaxa

First, read the medication leaflet that comes with this medication. Go through each section. You must understand the information in the printed guide. If you have any questions, you may direct your queries to your doctor or healthcare provider.

Take Pradaxa orally, with or without a meal. Drink a full glass of water afterward. In addition, swallow this drug and do not split or cut this capsule. If you do so, this will release the drug in the system all at once, thus, increasing the side effects.

Make sure to take this medication regularly. Do not alter your Pradaxa dosing or stop taking it without the advice of your physician. Your dosing would depend on factors like medical condition, response to treatment, kidney function, and other drugs you are taking.

If you are taking Pradaxa to prevent blood clots after hip or knee replacement surgery, take it exactly as prescribed by your doctor. Do not take antacids 24 hours after surgery because it may lessen the efficacy of this medication. If you experience stomach upset, take Pradaxa with food.

What are the side effects of Pradaxa?

Common side effects of Pradaxa:

  • Nausea
  • Heartburn
  • Indigestion
  • Stomach pain
  • Diarrhea
  • Easy bruising

Severe side effects of Pradaxa:

  • Severe heartburn
  • Persistent vomiting
  • Unusual swelling
  • Prolonged bleeding
  • Blood in the urine
  • Black or bloody stool
  • Severe headache
  • Fainting

Most people who are taking this drug experience mild adverse effects that resolve on their own. However, if you experience serious adverse reactions, discontinue taking Pradaxa, consult your physician, or immediately alert your healthcare provider.

Warnings and Precautions

Look out for possible allergic reactions when you take this drug. Do not take Pradaxa if you have a known allergy to dabigatran or any inactive ingredients this capsule may contain. Seek emergency care when you observe itchiness, red patches on the skin, severe headache, swelling of the face, and breathing difficulty. It is important to inform your physician about your medical condition or if you have a history of heart disease, kidney disease, liver disease, stroke, blood disorder, bleeding problem, or frequent fall/injury. Some conditions or medications you are taking, including supplements, may affect how you respond to the treatment.

As Pradaxa may cause heavy bleeding, be cautious when using sharp objects like knives or nail cutters. Also, use an electric razor when shaving and a toothbrush with soft bristles when brushing